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Clinical Trials
HIP ATTACK II – HIP Fracture Accelerated care and Treatment track II
HIP fracture Accelerated surgical TreaTment And Care tracK 2 (HIP ATTACK-2) Trial.
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A multi-center randomized controlled trial to determine whether accelerated surgery for hip fracture in patient with acute myocardial injury is superior to standard care in reducing death at 90 days after randomization.
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Inclusion criteria:
1) age ≥45 years;
2) diagnosis of hip fracture during working hours with a low- energy mechanism requiring surgery;
3) troponin elevation (at least one troponin measurement above the upper limit of normal occurring from the time of hip fracture to the time of randomization)
Exclusion criteria:
1) taking a therapeutic-dose of an anticoagulant for which no reversing agent is available and the anesthesiologist or surgeon believe surgery within 6 hours of eligibility criteria met would not be safe;
2) patients on a therapeutic vitamin K antagonist with a history of heparin induced thrombocytopenia (HIT);
3) patients with peri-prosthetic fracture, open fracture or bilateral fractures;
4) patients requiring an emergency surgery for another reason (e.g., subdural hematoma);
5) patients with acute myocardial infarction deemed to be clinically unstable, with a mechanical complication (i.e., acute papillary muscle rupture, ventricular septal defect), ST elevation myocardial infarction, or cardiogenic shock;
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V-STRUT©, a vertebral implant
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V-STRUT©, a vertebral implant This device is used to treatment of vertebral compression fractures (occurs when one or more bones in the spine weaken and crumple) The V-STRUT© device is a medical device that has received FDA clearance to treat these compression fractures.Circumferential vertebral RECONSTRUCTion of osteoporotic compression fractures using a novel bipedicular peek implant (RECONSTRUCT STUDY)
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In order for the study participant to be considered for enrollment, the patient must meet all of these parameters:
- Age > 50
- Osteoporotic compression fractures of the thoracolumbar spine (T9 – L5)
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