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Clinical Trials
CHAP Follow-Up Study
Pregnancy as a Window to the Future: Outcomes of Antihypertensive Therapy and Superimposed Preeclampsia in Pregnant Women with Mild Chronic Hypertension.
Study Coordinator
Monica Hosler
email:
Monica.Hosler@sluhn.org
phone: 484-658-4567
Close
This study is a long-term maternal outcomes study among women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia.
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Inclusion Criteria:
All women with mild CHTN who were randomized into CHAP between 2015 and 2021.
- Recall CHAP Inclusion criteria were: Confirmed mild CHTN (either new/untreated with BP 140 – 159/90-104 mmHg OR known monotherapy with BP ≤ 159/104 mmHg); Singleton live fetus; Gestational age < 23 weeks
- Recall CHAP Exclusion criteria were: Severe CHTN (recurrent BP ≥ 160/110 mmHg or on 2 or more antihypertensive drugs); Allergy to labetalol and nifedipine; Known secondary cause for CHTN; Current or prior CVD; Imminent threat to the fetus (major anomaly, FGR, membrane rupture)
Exclusion Criteria for follow-up study:
- Declined to be contacted for the follow-up study or cannot be contacted
- Sites that are unable to participate in the follow up
*If pregnant, follow-up for required in-person visit will be deferred until at least 12 weeks postpartum but this is not an exclusion
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Junonia Study
One in eight women experience postpartum depression (PPD). Many go undiagnosed and untreated. Effective diagnosis, treatment, and management of postpartum depression (PPD) benefits both the mother and the child.
Study Coordinator
Monica Hosler
email:
Monica.Hosler@sluhn.org
phone: 484-658-4567
Close
To evaluate the effect of care coordination on PPD outcomes among postpartum women who screened at risk for PPD and their clinicians’ knowledge, attitudes, beliefs, and practices concerning PPD.
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Inclusion criteria. English-speaking postpartum women 18 to 55 who delivered a live baby more than 4 weeks but less than 6 months from time of enrollment and received an EPDS score of 10+ when screened at more than 4 weeks but less than 6 months.
Exclusion criteria. Postpartum women who delivered less than 4 weeks or more than 6 months ago or were screened outside of this time period; women who experienced a stillbirth or pregnancy loss during the last pregnancy; women being treated for suicidal ideation or postpartum psychosis at the time of screening.
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