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SLUHN Joins National Study on New Shoulder Replacement Technology

December 30, 2025

DrCarolan

Dr. Gregory Carolan, an orthopedic surgeon with St. Luke’s Orthopedic Care, performed the first INHANCE procedure in the Lehigh Valley at St. Luke’s Orthopedic Hospital at the West End Campus. 

St. Luke’s University Health Network has been selected as the only health care system in the Lehigh Valley, and one of just a few nationwide, to take part in a major clinical trial studying a new shoulder replacement design called the INHANCE™ Shoulder System by DePuy Synthes.

This research will evaluate the safety and effectiveness of the INHANCE Shoulder System, which uses a stemless design instead of the traditional metal stem placed inside the arm bone. By removing the stem, the procedure may help preserve more natural bone and reduce bone loss, which could be important for patients who might need another surgery in the future.

The study is for patients who need a reverse total shoulder replacement because of a gross rotator cuff deficiency and severe pain and loss of function caused by conditions like osteoarthritis. These issues can make everyday activities difficult and greatly affect quality of life. Participation in the study is a decision made together by the patient and surgeon.

Dr. Gregory Carolan, an orthopedic surgeon with St. Luke’s Orthopedic Care, performed the first procedure in the Lehigh Valley at St. Luke’s Orthopedic Hospital at the West End Campus. DePuy Synthes invited Dr. Carolan to join the study because of his national reputation and extensive experience with complex shoulder surgeries.

“We are excited to be part of this important research,” said Dr. Carolan. “The stemless design could be a big step forward in shoulder replacement because it preserves more of the patient’s natural bone, which is especially important for long-term results.”

St. Luke’s participation in this study highlights its commitment to bringing advanced orthopedic care to the region.

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