Synopsis: You are being asked to participate in this research study because you have thrombocytopenia and are scheduled to undergo an operation to a site such as your eye, brain, etc. or an operation with a high risk of bleeding. Thrombocytopenia is when your blood has a lower than normal number of blood cells called platelets. Platelets travel through your blood vessels and stick together to help reduce any bleeding that may happen if a blood vessel is damaged. When your blood has too few platelets, mild to serious bleeding can occur inside your body (internal bleeding) or from the surface of your skin (external bleeding), especially during or after an operation.
The purpose of this research study is to:
- test the safety and effectiveness of the study drug, avatrombopag, in subjects with thrombocytopenia undergoing an operation
- test the effect of the study drug, avatrombopag, on the need for platelet transfusions in subjects with thrombocytopenia undergoing an operation
- test the effect of the study drug, avatrombopag, on bleeding in subjects with thrombocytopenia undergoing an operation
This is a research study to test an investigational drug, avatrombopag. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA) for this treatment.
Because this is a research study, avatrombopag will be given to you only during this study and not after the study is over.
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